Clara Bilbao

GAIKER, four decades of technological innovation

Interview with Santiago Rementeria, General Manager of the Centre

GAIKER is celebrating its 40th anniversary this year. What would you say have been the most important milestones in the centre's history since 1985?

    GAIKER was set up in 1985 as a non-profit association promoted by the Provincial Council of Bizkaia for the technological development of new materials, and in 1992 it merged with BIOTEK, a biotechnology group also set up by the Provincial Council in 1988. In 1993, we were granted the status of Supervised Entity by the Basque Government, and subsequently became a member of the Basque Association of Technology Centres (EITE). In 1997, we changed our legal and corporate model and became a private non-profit foundation. In 2005, we were founding members of the IK4 Research Alliance and in 2019 we joined the Basque Research and Technology Alliance (BRTA). These milestones of a corporate nature were interspersed with strictly technological ones and with others such as the coordination of the first international project (1991) and the establishment of our current location in Zamudio (1993).

    How has GAIKER's mission evolved since its foundation to the present day? What contribution has GAIKER made to the region's business and technology fabric?

    From the outset, the aim was to “help companies to increase their competitiveness”. Our mission continues to be to promote the use of technology as a key tool to contribute to increasing the competitiveness of the business sector, through our own R&D and the transfer of knowledge and experience acquired from developing innovative solutions for companies.

    This is the type of activity we have always carried out with our customers (more than 4,000 companies in total), which has resulted in almost 13,000 collaborations, including around 1,200 R&D projects. We have also registered about 100 patents and launched around 20 technology-based spin-offs in conjunction with these companies. We also contribute to business competitiveness by organising training courses on our specialist technologies and transferring qualified research staff to Basque industry.

    At one of the most disruptive moments in history, what are GAIKER's technological plans for the coming years?

    From a technological point of view, there have been more disruptive times than the present, although it is undeniable that we are currently experiencing a period of change. We are committed to strengthening our specialisation in disciplines related to the circularity of materials, sustainable manufacturing processes and the bioeconomy, incorporating digital technologies, sensorisation, artificial intelligence and robotics, among others. Moreover, the shift we are experiencing in the R&D priorities of state institutions as a result of the geopolitical context, and which we also expect to see in European institutions, is leading us to broaden the range of applications for the technologies we are developing, with an impact on sectors such as security, aeronautics and space.

    How do they fit into the centre's strategic plan for 2024-2027?

    GAIKER's 2027 strategy strengthens our commitment to contributing to the technological priorities of the Basque Country and Europe, with a primary focus on technology transfer to businesses. More specifically, our objectives are aligned with the Basque Country Industry Plan 2030 recently presented by the Basque Government.

    We are committed to a set of scientific and technological areas of specialisation in which we are looking to establish ourselves as a centre of excellence. We do not aspire to be experts in everything, but to focus on a number of core technologies and to have stable, first-class partners for other potentially ancillary technologies.

    In the area of composites and functional polymers, we will work towards achieving more circular materials, taking advantage of the intrinsic value of plastic and composite recycling streams and incorporating bio-based materials, additives and biodegradable materials, their formulation and advanced characterisation. This is all aimed at reducing our carbon footprint and replacing fossil fuels. In another line of work, we will look at developing state-of-the-art polymeric materials with built-in sensing capabilities, and haptic and piezoresistive characteristics. Developments will be supported by digitalised production processes, where we are committed to delving deeper into process simulation and monitoring, and structural calculations. We will also strengthen our capabilities with regard to advanced recycling technologies through the use of AI, new developments in spectroscopic identification techniques, and various chemical and enzymatic recycling methods. In the field of biotechnology, we will delve deeper into biomedicine, with a particular focus on the pharmaceutical and dermocosmetic sectors as specialists in the development and safety of new ingredients and products, in industrial microbiology, developing new environmental technologies centred on ecotoxicology and the bioremediation of water and soil, and in state-of-the-art amplification techniques for designing medical devices for pathogen detection.

    Although some of these lines were previously considered to be separate from one another, we are now seeing more and more opportunities for multidisciplinary integration in the areas where they overlap, leading to synergies that promote circularity and the bioeconomy.

    What targets have been set for its completion?

    On the revenue side, the objective is to continue on the growth path of recent years, aiming for an average annual increase of 7%. Last year was the first year of the plan, and we grew 12% over the previous year. The increase will mainly come from contract revenue, with public funding accounting for a smaller share. We also expect to maintain a level of investment of around 1.5 million euros per year. By the end of the period, we expect to have around 140 staff members, more than 80% of whom will be research personnel.

    Of the projects the centre is working on at the moment, could you cite a few that reflect these commitments?

    Below are some examples of industrial transfer, which is ultimately our main purpose. Eight companies are collaborating on the CICLO project, and we are coordinating the contributions of the six technology actors involved. The aim is to recycle and recover wind turbine blades and other components used in the construction of wind turbines, and to develop new materials (polymer matrices) that can be recycled more easily. This promotion of the circular economy is also evident at POST-AUTO, where we are developing technologies to recycle and process post-consumer plastic materials from the automotive sector so that they can be recovered and reused in new vehicles. At MAGIC, we are working individually for a food company to chemically recycle heavily coloured PET bottle waste, which allows new bottles to be manufactured from the synthesis of the monomers resulting from depolymerisation. In the field of biomedicine, one example of our work is organ regeneration, where we are contributing to the RECURE project to validate in vitro biological safety as part of the development of a biodegradable endoprosthesis for ureteral reimplantations.

    GAIKER is establishing itself as a European leader in several fields. After achieving record figures in 2024 for involvement in European consortia and leading projects in the European Horizon programme, what projects is the centre working on in 2025?

    We collaborate in international consortia with a focus on topics related to the circular economy, eco-innovation, safe-and-sustainable-by-design methodologies, and the biohealth sector. This year, we have been involved in more than a dozen Horizon Europe projects, leading three of them related to sustainable polymers: ECORES WIND, the aim of which is to develop new circular resins for use in wind power generation structures; BIOSAFIRE, which focuses on developing bio-based fire retardant materials; and E-OILÉ, which is geared towards designing and validating safe and biodegradable packaging solutions. Furthermore, we are involved in the FASTER-H2 project to design the rear fuselage of a new medium-range aircraft that will be hydrogen-compatible, a project coordinated by Airbus as part of the Clean Aviation aeronautical development programme.

    Following 40 years in business, what are GAIKER's objectives for the next decade?

    Our main objective has been to consolidate our position as a medium-sized, highly specialised centre that masters technologies of industrial interest for our business environment, with a positive impact on our customers' activities and a commitment to the challenges facing society. To this end, we have a growing number of leading researchers in their respective fields who enjoy an attractive working environment from a professional point of view. By the time it celebrates its fiftieth anniversary, GAIKER will maintain a balance between training and technology transfer efforts, exploit synergies between its scientific and technological departments, and be a leader in several areas of applied research and development. For example, this will apply to technologies and processes for smart sorting, identification, recovery and circularity of materials, both from conventional waste streams and those associated with renewable generation, electric mobility, or key raw materials. It will also apply to the development, analysis and circularity of all types of plastic or polymer-based materials, aiming for sustainable processes, less dependence on hydrocarbons and less waste going to landfill. We will have extensive experience in developing and applying new approach methodologies (NAMs), developing technologies that allow alternatives to traditional animal testing to be used to study biological functions and human diseases, such as new in vitro models, organotypic cultures, 3D tissue models, in silico models and the use of microfluidics to develop organ-on-chips, all combined with the use of high content screening (HCS) platforms. By 2035, we will be firmly established in Europe and, following the trend of recent years, we will have gained the trust of new large companies and SMEs alike to tackle the technological challenges of the future together.

    Biological parameters under control

    GAIKER develops and uses a variety of advanced tools to ensure precision, reliability and efficiency when analysing and monitoring biological parameters.

    Our main tools:

    We have developed laboratory-scale devices in our field of biosensing that can be adapted for verification and use in the field:

    • Test portátiles basados en tecnología lateral flow (test rápido de antígenos) que permiten detectar analitos in situ, sin necesidad de equipamiento y por personal no cualificado.
    • Sensores y dispositivos point of test basados en la amplificación de marcadores genéticos específicos utilizando técnicas ultra-rápidas de amplificación isoterma alternativas a la PCR.

    We also use the following in our mass sequencing work:

    • Metagenomic tools. We use mass sequencing technology to carry out metagenomic analyses by studying target genes (16S, ITS, etc.) in microbial communities.  

    This tool allows us to identify and characterise microbial diversity in a wide variety of human, environmental and industrial samples, providing accurate, reproducible information on the composition and abundance of the microorganisms present.

    Areas of application

    GAIKER provides cutting-edge technological solutions to meet the specific needs of industrial sectors.

    • Health
    • Environment
    • Food
    • Cosmetics
    • Bioremediation

    More information: info@gaiker.es

    BIWIN2, another step towards sustainability in the Basque Country

    The BIWIN2 project, coordinated by GAIKER, will generate knowledge on sustainable processes to turn agri-food and agricultural waste into biodegradable materials and micro-nano- cellulose reinforcements.

    The BIWIN2 project “Sustainable bioprocesses and processes, with potential scalability, to obtain materials of industrial interest (biopolyesters and bio-reinforcements) from waste biomass”, led by the GAIKER technology centre, a member of the Basque Research & Technology Alliance (BRTA), will be another step towards sustainability in the Basque Country.

    The recovery of biomass, especially local waste biomass, and conversion into new materials is a key area of research to exploit renewable natural resources and generate sustainable products with applications in various industrial sectors. This process requires the development of technologies that optimise the conversion of waste into high-value raw materials, contributing to the creation of regional value chains and manufacturing of industrial products, all with a focus on minimising environmental impact.

    This is the context in which the BIWIN2 project is created – an essential research project that aims to generate knowledge on sustainable processes to use agri-food and agricultural waste to develop biodegradable materials (medium-chain polyhydroxyalkanoates) and micro-nano-cellulose reinforcements. Specifically, it focuses on waste from the winemaking industry because of its availability to be processed and its high added value, since as well as providing lignocellulosic waste, it is rich in sugars.

    Although the focus of the project is on bioprocesses, fractionation processes and chemical processes to achieve TRLs 3-4, with emphasis on their sustainability, the ultimate goal is for the knowledge to be potentially scalable within a limited time frame and in the industrial environment of the Basque Country in order to facilitate the availability of new resources in value-added applications. For this reason, proofs of concept have been defined in leading sectors such as biodegradable and safely recyclable food packaging, and the automotive coatings/paints sector.

    This project, funded by the Basque Government as part of the ELKARTEK 2025 Grant Programme for Collaborative Research in Strategic Areas, responds to current environmental needs and European policies, which promote the use of more sustainable processes and materials. Its aim is to promote a circular economy model, offering alternative and complementary solutions to the use of recycled raw materials. Thanks to policies to boost the bioeconomy and circular economy, the market for so-called bioproducts is being promoted as an alternative to petroleum products.

    In addition to GAIKER, other organisations such as NEIKER, TECNALIA, CEIT, BCMATERIALS, and the BIOMAT group of EHU are taking part in BIWIN2. Together they create a multidisciplinary group of university centres and departments, which has already been collaborating since the Circular Biobased project in 2022. The aim is to integrate complementary lines of work to accelerate the deployment of the bioeconomy strategy based on abundant biomasses in the Basque Country.

    Subsidised by the Basque Government

    Safety of medical devices and topical medications

    GAIKER leads the development of alternative methods for for assessing the safety of medical devices and drugs

    At GAIKER, we are proud to offer advanced, ethical solutions regarding the safety of healthcare products and drugs. We carry out state-of-the-art in vitro and ex vivo studies to assess the safety of these products at various stages of their development, from pre-clinical to clinical phases. This approach allows us to detect potential risks early, thereby ensuring the safety and efficacy of products for the end consumer.

    One of the cornerstones of our work is biocompatibility, which we assess without the need for animal testing. This approach not only helps minimise the use of animals in experimentation, but also contributes to the development of more ethical alternative methods, in line with the principles of the 3Rs (replacement, reduction and refinement).

    We have state-of-the-art tools and equipment that enable us to provide a wide range of tests that are adapted to customer needs:

    • Safety tests
    • Cytotoxicity tests
    • ADME-tox studies covered by a guarantee of good laboratory practices (GLPs)
      • Absorption
        • Skin absorption (OECD 428). Franz Diffusion Cells
      • Organ-specific toxicity
        • Organo-specific toxicity tests
      • Toxicity mechanisms
        • Tailor-made tests: apoptosis/necrosis, oxidative stress, inflammation, DNA damage, intracellular calcium, etc.
      • Genotoxicity
        • Ames test (OECD 471)
        • Mutagenicity in mammalian cells (OECD 476)
        • Micronucleus test (OECD 487)
      • Eye tests
        • Eye irritation and damage (OECD 492, Het-Cam)
      • Skin tests
        • Skin corrosion/irritation (OECD 431, OECD 435, OECD 439)
        • Phototoxicity (OECD 432)
        • Oral, nasal, vaginal and gingival irritation

    More information – info@gaiker.es

    We are researching new solutions to boost the circular economy in renewable energy

    The CICLO Transmissions project focuses on developing technological solutions for recycling and recovering composite materials that are used to build wind turbines.

    Currently, 83% of the materials that make up a wind turbine can be recycled or reused. However, blades are extremely challenging because of their heterogeneous composition and the fact that they contain materials that are difficult to treat and separate properly using conventional recycling processes. The CICLO project (2025-2028) has been created with the aim of providing a solution to this challenge. Eight companies and six research centres are taking part in this project, including the GAIKER Technology Centre, which is a member of the Basque Research & Technology Alliance (BRTA), and coordinator of the AEI consortium.

    The main goal of this project is to conduct research into new technological solutions to boost the circular economy in the field of renewable energy, specifically for recycling and recovering blades and other composite components used to build wind turbines, such as nacelles, electrical cabinets, etc. at the end of their life cycle. In addition, research will be carried out into the development of alternative materials that are easier to recycle compared to existing materials, in the form of recyclable polymer matrices.

    The project aims to optimise the recovery of fibres and by-products from thermal and chemical recycling, so that at least 90% of the recycled fibre is recoverable and the efficiency in the recovery of by-products from recycling exceeds 75%. It also aims to reduce the formation of organic pollutants in thermal processes by 50% and to improve the enzymatic degradation of epoxy resin, polyester and polyurethane. These developments will strengthen the sustainability and efficiency of composite recycling and promote the creation of second-generation structural materials with a 100% recycled content, integrating high percentages of recycled fibres.

    GAIKER, as an expert in sustainable composites and recycling and circular economy, is coordinating the project’s AEI consortium, and will be in charge of researching technologies for remodelling, joining and functionalising fibre-reinforced composite plates extracted from the blade for new applications. It will also explore chemical recycling processes to recover reinforcement fibres and polymer matrices, including recycled reinforcement fibres in BMC and SMC intermediate products and seeking alternative material recovery of liquids from such recycling for the formulation of new resins. Research will also be carried out into the recovery of lightweight blade components (foams and balsa wood) by developing a new generation of lightweight cores and new recyclable and sustainable high-performance composites, using infusion technology, which also incorporate recovered fibre and lightweight cores.

    Subsidised by the Centre for the Development of Industrial Technology (CDTI by its Spanish acronym) and backed by the Ministry of Science and Innovation within the Transmissions 2024 Programme (PLEC2024-011215), CICLO, using an integrated approach that includes separation, extraction, recycling, formulation and processing, aiming to recover practically 100% of composite materials.

    Project PLEC2024-011215 funded by MICIU/AEI/10.13039/501100011033 and by ERDF, EU.

    We are committed to AI to transform the design and manufacturing processes of composite aerostructures

    The European pAIramid project will develop a virtual testing platform that will guide the design and processing of composite materials in the characterisation pyramid.

    The GAIKER technology centre, a member of the Basque Research & Technology Alliance, BRTA, is participating in the European project on 'Al-based testing pyramid virtual certification of next-gen composite aerostructures', pAIramid.

    This research, which began in 2024 and will last for 45 months, aims to advance tools and methodologies based on artificial intelligence (AI) to transform the design and manufacturing processes of aeronautical composite structures, using sustainable thermosetting and functionalised thermoplastic resins.

    The aerospace industry faces major challenges when it comes to certifying composite aerostructures, as it is a complex and costly process based on the traditional pyramid framework, in which each level undergoes labour-intensive sequential testing from materials to complete aerostructures.

    In order to provide a solution to these challenges, pAIramid will create a virtual testing platform to guide the design and processing at all levels of the characterisation pyramid (from the material specimen, the element, the component and the complete structure), optimising virtual certification, accelerating innovation and improving design decision-making. The project will also develop functionalised thermoset and thermoplastic resins and optimise the LRI (Liquid Resin Infusion) and FDM (Fused Deposition Modelling) manufacturing processes for the cost-effective and scalable production of complex functionalised parts..

    This innovative approach seeks to replace costly physical testing with high-fidelity simulations and data-driven insights, making certification a more streamlined, efficient and connected process.

    pAIramid involves 13 strategic partners from seven different countries, including GAIKER, an expert in the formulation and design of composites, whose role focuses on the development of functionalised thermoset resins and their characterisation for use in two of the four aerospace case studies in the project: in the structure of the aircraft door and in the front edge of the wing.

    As part of the European Union's HORIZON programme, this research represents a crucial step towards the digital transformation of the European aerospace industry, setting a new standard for the development of more sustainable and efficient aircraft.

    Project partners

    The pAIramid project is made up of a consortium that includes research and technology centres, such as IKERLAN S. Coop. (project coordinator), GAIKER, IRT Jules Verne and INEGI, as well as prestigious universities, such as the University of Girona and Brunel University London. It also has industrial partners from the aerospace sector, such as Collins Aerospace-RTX, Turkish Aerospace, POTEZ Aeronautique and SOFITEC Aero, and companies specialising in consultancy and technological services such as MECA, LKS Next and Zabala Innovation Europe.

    More information: https://pairamid.eu/

    This project has received funding from the European Union's Horizon Europe research and innovation programme under grant agreement No. 101192736.