GAIKER specialises in the assessment of the safety and efficacy of molecules, compounds or final products using different models. Our in vitro and ex vivo tests on human skin models provide quality solutions for the dermo-cosmetic, nutraceutical and pharmaceutical sectors. We have the capacity to perform customised studies on the mechanisms of action of active ingredients, as well as studies based on conventional protocols and GLP requirements in accordance with international guidelines, such as the FDA or the EMA.
Our work includes tube tests, cell cultures (keratinocytes, dermal fibroblasts, immune system cells…), 3D models and ex vivo human skin explants. Moreover, we have well-equipped laboratories for cell culture, molecular biology, proteomics-genomics (including Microbiome analysis) with state-of-the-art equipment, such as: scanning electron microscope (SEM), confocal microscope, our cell bank, biofilm reactor, flow cytometer, Franz cells, UPLC…
Techniques have been developed to generate a series of skin models with different aetiologies, such as sensitive skin, psoriasis, atopic dermatitis, reddish skin etc., presenting the same determining characteristics of skin with a specific pathology. We also have the capacity to develop organotypic cultures with specific pathologies that enable us to simulate skin models that reproduce the characteristics of ulcerated or burnt skin.
