Harmonisation and Standardisation of test methods for nano and advanced materials

    Fecha: 22-23 de Noviembre de 2023

Presentación Building on NanoHarmony and NANOMET's foundation, this online workshop, a collaboration between Horizon Europe projects MACRAMÉ, nanoPASS, and iCare along with the Malta Initiative, delves into the evolving landscape of OECD Test Guideline developments for nanomaterials. Participants will receive information on ongoing OECD TG developments for nanomaterials as well as the Malta Initiative outlook on the future of TG developments within a European Test Method Strategy. New developments towards harmonisation and standardisation of in vitro testing will be presented and their integration in regulatory risk assessment will be discussed. We will present the status and developments of standards for characterisation of Advanced Materials, as illustrated by graphene materials. Roundtables will give stakeholders the opportunity to provide input into the development and inclusion of new methods into regulatory risk assessment.

 

 

Day 1- 22 November 2023
10.20 – 10.40 Status of OECD TG developments for nanomaterial. Mar Gonzalez (OECD)
10.40 – 11.00 The European Partnership on Metrology (EPM) and VAMAS: Opportunities for Pre-Standardisation Activities. Georges Favre (LNE)
11.0 0– 11.20 Contribution of ECVAM towards Validation and regulatory Acceptance of in vitro Methods. Valerie Zuang (ECVAM)
11.20 – 11.40 Approach Methodologies (NAMs) and how to bridge them into regulation. Andrea Haase (BfR)

Developments of in-vitro Models and bridging them towards Standardisation / Harmonisation and Regulation
11.40 – 12.00 MACRAMÉ´s Approach towards the Harmonisation of in vitro/ex vivo Models for Inhalation Toxicology. Tommaso Serchi (LIST)
12.00 – 12.40 Lunch Break
12.40 – 13.00 The Work planned in nanoPASS to support the Weight of Evidence of AOP302 Lung Surfactant Function Inhibition Leads to reduced Lung Function. Jorid Birkelund Sørli (NRCWE)
13.00 – 13.20 iCare’s Approach towards the Harmonisation of human and ecotox Models for Neurotoxicity. Alberto Katsumiti (GAIKER)
13.20 – 13.40 Strategies to increase the technical Quality of new Approach Methodologies (NAMs) and Nanoecotoxicology Tests. Elijah Petersen (NIST)
13.40 – 15.00 Round Table on Harmonisation & Standardisation of in vitro Models and how to bridge them into Regulation. Chair: Blanca Suarez Merino (NIA)
15.00 – 15.15 Round-up of Day 1

Day 2 - 23 November 2023
10:10 – 10.30 OECD Test Guidelines for Nanomaterials: Support and future steps towards TG development by Malta Initiative and NanoHarmony. Elisabeth Heunisch (BAuA)
10.30 – 10.50 Status and Challenges in Regulation of Graphene. Eric Bleeker (RIVM)

Session on (Pre-)Standardisation Activities for pristine Graphene
10.50 – 11.10 ISO and VAMAS Activities on (pristine) Graphene. Charles Clifford (NPL)
11.10 – 11.30 Achievements of the Graphene Flagship and the Way forward. Jörg Radnik (BAM)
11.30 – 11.50 Framework on Characterisation. Terance Barkan (Graphene Council)
11.50 – 12.30 Lunch Break

Activities on Determination of Graphene in complex Media
12.30 – 12.50 Interlaboratory Study of graphene using TGA. Dusan Losic (University of Adelaide)
12.50 – 13.10. Simultaneous Screening of the Stability and Dosimetry of Nanoparticles Dispersions using SMLS for in vitro Toxicological Studies. Guillaume Lemahieu (Formulaction)
13.10 – 13.30 Approaches to identify and measure the Stability of Graphene in complex Media. Fanny Caputo (LNE)
13.30 – 15.00 Round Table on the Needs for Characterisation and Test Method Developments for Graphene. Chair: Georges Favre (LNE).
15.00 –1 5.15 Workshop Wrap-Up – Conclusions – Outlook. Steffi Friedrichs (AcumenIST)
 

On-line

 

10.00 – 15.15